MechanismofAction相关论文
随着人口老龄化和社会经济的发展,慢性创面发病率日益增高,同时烧创伤发病率仍处于较高水平,使得创面修复成为临床日益关注的领域。胸......
Malassezia species are common pathogenic fungus that causes several skin diseases, which have a certain rate of resistan......
认知功能障碍严重影响患者生活质量,临床上常见于脑缺血疾病、脓毒症及术后等,其病因包括脑内调节分子表达异常、脑组织缺血性损伤及......
慢性肾脏疾病相关性瘙痒是晚期慢性肾脏疾病(chronic kidney disease,CKD)和终末期肾病(end-stage renal disease,ESRD)患者常见的......
急性肺损伤具有高发病率及高病死率,但目前临床尚无对于急性肺损伤的特效治疗措施,因此如何预防和治疗急性肺损伤仍是目前研究的重要......
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Large numbers of free radicals emerge under the diseases,oxidative stress and special physiological conditions,which lea......
目的 The differential expression of Long non-coding RNAs(lncRNAs)in pterygium werescreened by gene chip technology,and t......
Immune responses to vaccines involving a combined antigen-nanoparticle mixture and nanoparticle-enca
Background and Objective: Biodegradable polymer-based micro/nanoparticles have been extensively investigated as vaccine ......
Asthma is a chronic inflammatory disorder of airways that affects approximately 300 million adults and children worldwid......
Insights into the mechanism of Huangqi decoction(HQD)by means of metabolomics and network pharmacolo
Huangqi decoction(HQD)consists of Radix Astragali(RA)and Radix Glycyrrhizae(RG)in a ratio of 6:1,which has been used to ......
目的:分析生血宝合剂治疗肾性贫血的临床效果及作用机制?方法:研究对象选取120例本院于2020年03月-2021年03月纳入的肾性贫血患者,......
Objective: To explore the effect of Sini Decoction plus Ginseng on COVID-19 based on network pharmacological analysis. M......
透明质酸酶是可以特异性降解透明质酸的一类糖苷酶,主要有6个种类,其中对透明质酸酶-1(HYAL-1)与透明质酸酶-2(HYAL-2)的研究较深入,......
Objective:Based on the technology and method of network pharmacology,to explore the active components and specific mecha......
全身动脉粥样硬化的发生是从颈动脉粥样硬化开始的,在治疗颈动脉粥样硬化的过程中采用中医药疗法对脑、肾、心等脏器的病理损害以及......
μ阿片受体( MOR)是一种G蛋白偶联受体,在痛觉传导区以及与情绪和行为相关的区域广泛存在,影响着动物的神经反应和行为表现。有研究发......
二肽基肽酶4(DPP-4)抑制剂通过延缓胰升糖素样多肽1(GLP-1)、糖依赖性胰岛素释放肽( GIP)降解而延长生理性GLP-1作用时间达到降低血糖的作用......
变应性鼻炎是临床常见的变态反应性疾病,其发病机制与细胞因子密切相关。细胞因子是一个庞大的小分子蛋白家族,成员繁多,作用广泛。作......
Septin9是一类具有三磷酸鸟苷酶活性的保守基因家族成员之一,与染色体分离、DNA 修复、迁移和凋亡等许多细胞功能有关。 Septin9与......
MicroRNA是一组小分子单链RNA,其在转录后水平参与基因表达调控.近年来,microRNA在心血管疾病中的研究日益丰富,对其认识也日趋完......
急性胰腺炎(acute pancreatitis,AP)是外科常见急腹症之一.病理上分为急性水肿性胰腺炎和急性出血坏死性胰腺炎,后者病情危重,病死......
目的:微小RNA( microRNA,miRNA,miR)为一类由20~26个核苷酸构成的高度保守的单链非编码RNA,在真核细胞中调控基因的表达。一种miRNA能同时......
Potentiating activity of rhein in targeting of resistance genes in methicillin-resistant Staphylococ
Objective: To investigate the synergistic effect between rhein (RHE) and oxacillin against Staphylococcus aureus (MRSA) ......
重复经颅磁刺激是一种无痛、无创伤的新型治疗和研究技术,在精神科领域的使用已趋于成熟,特别是近几年,重复经颅磁刺激治疗抑郁症的研......
Non-alcoholic fatty liver disease (NAFLD) is a liver disease characterized by ectopic liver steatosis and steatosis. It ......